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Your vet will know this when they administer the correct medication for your dog. In general, 1/2 a 4mg tablet or 5ml is prescribed for smaller Vets recommend giving your dog 2 to 4 milligrams of Benadryl per kilogram of weight but watch out for common overdose symptoms. refresh pm reviews Antihistamine Dosaging. Generic. Common Brands. Forms. 1-10lbs. lbs. lbs. lbs. 50lbs. How Often. Diphenhydramine. Benadryl. 25mg Tablet. 1/2 to The general dose of Benadryl (diphenhydramine) is 2 to 4 mg/kg up to three times day. If your dog weighs 25 lbs (11.3 kg) the dose of Benadryl would be 22.6mg This is just a general guideline, the general dose of Benadryl (diphenhydramine) is 2 to 4 mg/kg up to three times day. If your dog weighs
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