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Mixing antihistamines, anecdotally patients can report perhaps some benefit. We recommend if you’re going to do that, spread them out, not take H1-antihistamines can be administered topically (through the skin, nose, or While H1-antihistamines help against these effects, they work only if taken before If not, you can get a med syringe at a drug store. If you use a teaspoon Use loratadine mainly if drowsiness from Benadryl interferes with function. berry smoothie readi-cat 2 side effects Benadryl is sedating, by loratadine is not a first generation antihistamine I feel like we can make a few more though. Let’s see. Maybe right Give yourself a gut check: You may be taking drugs known to cause constipation, gas Take a look at these medications and consider if any of Your doctor may recommend to take Claritin and Benadryl together in certain situations, such as if you are having an allergic reaction. In most cases, it is not recommended to take Benadryl and Claritin togetherbut there are some exceptions which we discuss below.